Reproductive Rebel

Quick Fix or Quiet Crisis? The Hidden Costs of GLP-1s in Perimenopause with Alyx Coble-Frakes

• Adrienne Irizarry, HWH • Season 5 • Episode 4

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0:00 | 30:47

Perimenopause is already a wild ride for many women—hormones shifting, cycles changing, and the body sending signals we can’t ignore. Enter GLP-1 medications, marketed as quick fixes for weight management. But what happens when the “solution” comes with side effects that ripple through your hormones, gut, and emotional well-being?

In this episode, Alyx Coble-Frakes joins the Reproductive Rebel to unpack the unseen costs of GLP-1s during perimenopause. We explore:

  • How GLP-1 medications interact with perimenopausal bodies
  • Common and lesser-known side effects women experience
  • Why quick fixes may actually deepen long-term health struggles
  • Tools and approaches to support your body naturally through this life stage

This is your guide to seeing past the marketing hype, reclaiming bodily wisdom, and making choices that honor your health over convenience.

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